ArtNr |
E10-30178 |
Hersteller |
Enogene
|
Menge |
100ug/100ul |
Kategorie |
|
Typ |
Antibody |
Applikationen |
ELISA, Western Blot, Immunohistochemistry |
Specific against |
Human |
Host |
Mouse |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
MSI2H, MGC3245, FLJ36569, MSI2 |
Similar products |
MSI2 |
Lieferbar |
|
Background |
Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.Tissue specificity: Ubiquitous; detected at low levels. |
Research Area |
Autophagy antibody, Cancer, Cardiovascular, Cell Biology, Epigenetics and Nuclear Signaling, Developmental Biologys, Immunology, Drug Discovery Products, Metabolism, Neuroscience, Signal Transduction, Stem Cells |
Form of Antibody |
Ascitic fluid containing 0.03% sodium azide. |
Altername |
MSI2H, MGC3245, FLJ36569, MSI2 |
Immunogen |
Purified recombinant fragment of human MSI2 expressed in E. Coli. |
Applications information |
WB, IHC, ELISA. Not yet tested in other applications. |
Molecular Weight |
35kDa |
Recommended Dilutions |
WB: 1/500 - 1/2000, IHC: 1/200-1/1000, ELISA: Propose dilution 1/10000. |
Storage/Stability |
Store at 4C, for long term storage, store at -20C. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.