ArtNr |
BOS-EZ0502 |
Hersteller |
Boster
|
Menge |
For 5 plates, 96 wells each, reagents only, plates are not included |
Kategorie |
|
Typ |
Elisa |
Applikationen |
ELISA |
Specific against |
Mouse |
Sensitivity |
<10 pg/ml |
ECLASS 10.1 |
32160605 |
ECLASS 11.0 |
32160605 |
UNSPSC |
41116126 |
Alias |
E-selectin;CD62 antigen-like family member E;Endothelial leukocyte adhesion molecule 1;ELAM-1;Leukocyte-endothelial cell adhesion molecule 2;LECAM2;CD62E;Sele;Elam-1; |
Lieferbar |
|
Manufacturers Product Category |
EZ-Set™ ELISA Kits (Ab Pairs) |
Short Description |
Mouse sE-Selectin ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Mouse SELE in cell culture supernatants, serum and plasma (heparin, citrate). |
Description |
Mouse sE-Selectin ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Mouse SELE in cell culture supernatants, serum and plasma (heparin, citrate). |
Background |
E-selectin, also called endothelial-leukocyte adhesion molecule-1 (ELAM-1), is a cell surface glycoprotein expressed by cytokine-activated endothelium that mediates the adhesion of blood neutrophils. An increased expression of E-selectin has been observed in the arterial endothelium interacting with lymphocytes and macrophages in human atherosclerotic lesions. E-selectin plays a critical role in mediating tissue-specific homing of T cells into skin, and of primitive hematopoietic progenitor cells (HPCs) into bone marrow (BM). A structurally and functionally related group of genes, lymph node homing receptor (LHR), granule membrane protein 140 (GMP-140), and endothelial leukocyte adhesion molecule 1 (ELAM-1) are shown to constitute a gene cluster on mouse and human chromosome 1. The standard product used in this kit is recombinant mouse E-Selectin, excluding intercellular E-Selectin and transmembrane domain. It consists of totally 557 amino acids with the molecular mass of 85.8KDa. |
Gene Name |
SELE |
Immunogen |
Expression system for standard: NS0; Immunogen sequence: W22-P557 |
Cross-reactivity |
There is no detectable cross-reactivity with other relevant proteins. |
Sample Type |
cell culture supernatants, serum and plasma (heparin, citrate). |
Storage |
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
Anticoagulant |
heparin or citrate |
Gene Full Name |
E-selectin |
Molecular Weight |
66750 MW |
Protein Function |
Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis. |
Subcellular Localization |
Cell membrane ; Single-pass type I membrane protein. |
Protein Name |
E-selectin |
Sequence Similarities |
Belongs to the selectin/LECAM family. |
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