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Mouse sE-Selectin ELISA Kit EZ-Set™ (DIY Antibody Pairs) Europäischer Partner

ArtNr BOS-EZ0502
Hersteller Boster
Menge For 5 plates, 96 wells each, reagents only, plates are not included
Kategorie
Typ Elisa
Applikationen ELISA
Specific against Mouse
Sensitivity <10 pg/ml
ECLASS 10.1 32160605
ECLASS 11.0 32160605
UNSPSC 41116126
Alias E-selectin;CD62 antigen-like family member E;Endothelial leukocyte adhesion molecule 1;ELAM-1;Leukocyte-endothelial cell adhesion molecule 2;LECAM2;CD62E;Sele;Elam-1;
Lieferbar
Manufacturers Product Category
EZ-Set™ ELISA Kits (Ab Pairs)
Short Description
Mouse sE-Selectin ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Mouse SELE in cell culture supernatants, serum and plasma (heparin, citrate).
Description
Mouse sE-Selectin ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Mouse SELE in cell culture supernatants, serum and plasma (heparin, citrate).
Background
E-selectin, also called endothelial-leukocyte adhesion molecule-1 (ELAM-1), is a cell surface glycoprotein expressed by cytokine-activated endothelium that mediates the adhesion of blood neutrophils. An increased expression of E-selectin has been observed in the arterial endothelium interacting with lymphocytes and macrophages in human atherosclerotic lesions. E-selectin plays a critical role in mediating tissue-specific homing of T cells into skin, and of primitive hematopoietic progenitor cells (HPCs) into bone marrow (BM). A structurally and functionally related group of genes, lymph node homing receptor (LHR), granule membrane protein 140 (GMP-140), and endothelial leukocyte adhesion molecule 1 (ELAM-1) are shown to constitute a gene cluster on mouse and human chromosome 1. The standard product used in this kit is recombinant mouse E-Selectin, excluding intercellular E-Selectin and transmembrane domain. It consists of totally 557 amino acids with the molecular mass of 85.8KDa.
Gene Name
SELE
Immunogen
Expression system for standard: NS0; Immunogen sequence: W22-P557
Cross-reactivity
There is no detectable cross-reactivity with other relevant proteins.
Sample Type
cell culture supernatants, serum and plasma (heparin, citrate).
Storage
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Anticoagulant
heparin or citrate
Gene Full Name
E-selectin
Molecular Weight
66750 MW
Protein Function
Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis.
Subcellular Localization
Cell membrane ; Single-pass type I membrane protein.
Protein Name
E-selectin
Sequence Similarities
Belongs to the selectin/LECAM family.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: For 5 plates, 96 wells each, reagents only, plates are not included
Lieferbar: In stock
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