Recombinant Human CD38 Protein (His Tag)

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, CD38 antigen, CD38 molecule, CD38

Recombinant Human CD38 is produced by our Mammalian expression system and the target gene encoding Val43-Ile300 is expressed with a 6His tag at the C-terminus.

C-His

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20CC.

< 1.0 EU per ug as determined by the LAL method.

30.7 kDa

Supplied as a 0.2 um filtered solution of PBS; pH7.4.

CD38; also known as ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; is a Signal-anchor for type II membrane protein. CD38 is able to transform NAD+ to ADP-D-ribose and nicotinamide. It also can transform NADP+ to nicotinate-adenine dinucleotide phosphate and nicotinamide. CD38 is expressed at high levels in pancreas; liver; kidney; brain; testis; ovary; placenta; malignant lymphoma and neuroblastoma. Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate; the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.