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Recombinant Human Cathepsin Z Protein (His Tag)

Hersteller Elabscience
Kategorie
Typ Proteins
Specific against Human
Menge 50ug
Host Human Cells
ArtNr ELS-PKSH033443-50ug
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Alias Cathepsin Z, Cathepsin P, Cathepsin X, CTSZ
Synonym
Cathepsin Z, Cathepsin P, Cathepsin X, CTSZ
Storage
< -20CC
Protein Construction
Recombinant Human Cathepsin Z is produced by our Mammalian expression system and the target gene encoding Gly24-Val303 is expressed with a 6His tag at the C-terminus.
Sequence
Gly24-Val303
Fusion tag
C-6His
Accession
Q9UBR2
Shipping
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20CC.
Purity
> 95 % as determined by reducing SDS-PAGE.
Endotoxin
< 1.0 EU per ug as determined by the LAL method.
Stability and Storage
Store at < -20CC, stable for 6 months. Please minimize freeze-thaw cycles.
Mol Mass
32.5 kDa
AP Mol Mass
37 kDa
Formulation
Supplied as a 0.2 um filtered solution of 20mM HAc-NaAc; 150mM NaCl; pH 4.0.
Reconstitution
Please refer to the printed manual for detailed information.
Background
Cathepsin Z is a lysosomal cysteine proteinase and belongs to the peptidase C1 family. Human Cathepsin Z contains a singnal sequence; a propeptide and a mature chain. It exhibits bothcarboxy-monopeptidase and carboxy-dipeptidase activities. In contrast to cathepsin B; it does not act as an endopeptidase. Cathepsin Z is restricted to the cells of theimmune system; predominantly monocytes; macrophages and dendritic cells. It is expressed ubiquitously in cancer cell lines and primary tumors. Like other members of this family; Cathepsin Z may be involved in tumorigenesis.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50ug
Lieferbar: In stock
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