ArtNr |
ELS-PKSH032803-10ug |
Hersteller |
Elabscience
|
Menge |
10ug |
Kategorie |
|
Typ |
Proteins |
Specific against |
Human |
Host |
E.coli |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Neurotrophin-3, NT-3, HDNF, Nerve Growth Factor 2, NGF-2, Neurotrophic Factor, NTF3 |
Similar products |
Neurotrophin-3, NTF3, NT-3, HDNF, NGF-2, Nerve Growth Factor 2, Neurotrophic Factor |
Lieferbar |
|
Synonym |
Neurotrophin-3, NT-3, HDNF, Nerve Growth Factor 2, NGF-2, Neurotrophic Factor, NTF3 |
Storage |
according to manual |
Activity |
Immobilized Human NT-3 at 10ug/ml(100 ul/well) can bind Human TrkB-His(Cat: PKSH033579). The ED50 of Human NT-3 is 3.777 ug/ml . |
Protein Construction |
Recombinant Human Neurotrophin-3 is produced by our E.coli expression system and the target gene encoding Tyr139-Thr257 is expressed. |
Sequence |
Tyr139-Thr 257 |
Accession |
P20783 |
Shipping |
This product is provided as lyophilized powder which is shipped with ice packs. |
Purity |
> 95 % as determined by reducing SDS-PAGE. |
Endotoxin |
< 1.0 EU per ug as determined by the LAL method. |
Stability and Storage |
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80CC. Reconstituted protein solution can be stored at 4-8C for 2-7 days. Aliquots of reconstituted samples are stable at < -20C for 3 months. |
Mol Mass |
13.6 kDa |
AP Mol Mass |
14 kDa |
Formulation |
Lyophilized from a 0.2 um filtered solution of 20mM PB, 250mM NaCl, pH 7.2. |
Reconstitution |
Please refer to the printed manual for detailed information. |
Background |
Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors and is structurally related to beta-NGF, BDNF and NT-4. The NT3 cDNA encodes a 257 amino acid residue precursor protein with a signal peptide and a proprotein that are cleaved to yield the 119 amino acid residue mature NT3.The amino acid sequences of mature human, murine and rat NT-3 are identical. NT-3 selectively promotes the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.