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Recombinant Human Neurotrophin-3/NTF3 Protein (Active)

ArtNr ELS-PKSH032803-10ug
Hersteller Elabscience
Menge 10ug
Kategorie
Typ Proteins
Specific against Human
Host E.coli
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Neurotrophin-3, NT-3, HDNF, Nerve Growth Factor 2, NGF-2, Neurotrophic Factor, NTF3
Similar products Neurotrophin-3, NTF3, NT-3, HDNF, NGF-2, Nerve Growth Factor 2, Neurotrophic Factor
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Synonym
Neurotrophin-3, NT-3, HDNF, Nerve Growth Factor 2, NGF-2, Neurotrophic Factor, NTF3
Storage
according to manual
Activity
Immobilized Human NT-3 at 10ug/ml(100 ul/well) can bind Human TrkB-His(Cat: PKSH033579). The ED50 of Human NT-3 is 3.777 ug/ml .
Protein Construction
Recombinant Human Neurotrophin-3 is produced by our E.coli expression system and the target gene encoding Tyr139-Thr257 is expressed.
Sequence
Tyr139-Thr 257
Accession
P20783
Shipping
This product is provided as lyophilized powder which is shipped with ice packs.
Purity
> 95 % as determined by reducing SDS-PAGE.
Endotoxin
< 1.0 EU per ug as determined by the LAL method.
Stability and Storage
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80CC. Reconstituted protein solution can be stored at 4-8C for 2-7 days. Aliquots of reconstituted samples are stable at < -20C for 3 months.
Mol Mass
13.6 kDa
AP Mol Mass
14 kDa
Formulation
Lyophilized from a 0.2 um filtered solution of 20mM PB, 250mM NaCl, pH 7.2.
Reconstitution
Please refer to the printed manual for detailed information.
Background
Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors and is structurally related to beta-NGF, BDNF and NT-4. The NT3 cDNA encodes a 257 amino acid residue precursor protein with a signal peptide and a proprotein that are cleaved to yield the 119 amino acid residue mature NT3.The amino acid sequences of mature human, murine and rat NT-3 are identical. NT-3 selectively promotes the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10ug
Lieferbar: In stock
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