Recombinant Human CD300a/LMIR1 Protein (His Tag)

CMRF35-Like Molecule 8, CLM-8, CD300 Antigen-Like Family Member A, CMRF-35-H9, CMRF35-H9, CMRF35-H, IRC1/IRC2, Immunoglobulin Superfamily Member 12, IgSF12, Inhibitory Receptor Protein 60, IRp60, NK Inhibitory Receptor, CD300a, CD300A, CMRF35H, IGSF12

Recombinant Human Leukocyte mono-Ig-like receptor 1 is produced by our Mammalian expression system and the target gene encoding Leu18-Gln178 is expressed with a 6His tag at the C-terminus.

C-6His

This product is provided as lyophilized powder which is shipped with ice packs.

< 1.0 EU per ug as determined by the LAL method.

18.5 kDa

Lyophilized from a 0.2 um filtered solution of 20mM PB; 150mM NaCl; pH 7.2.

CD300A is a single-pass type I membrane protein that belongs to the CD300 family. CD300A consists of a 163 amino acid (aa) extracellular domain (ECD) with one Ig-like V- type domain; a 21 amino acid transmembrane segment; and a 98 amino acid cytoplasmic domain with tyrosine residues. CD300A is expressed not only by natural killer (NK) cells but also by T-cell subsets; B-cells; dendritic cells; mast cells; granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells; and to the down-regulation of mast cell degranulation.