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Recombinant Human Complement Factor B/CFB Protein (His Tag)

ArtNr ELS-PKSH032272-50ug
Hersteller Elabscience
Menge 50ug
Kategorie
Typ Proteins
Specific against Human
Host Human Cells
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Complement Factor B, C3/C5 Convertase, Glycine-Rich Beta Glycoprotein, GBG, PBF2, Properdin Factor B, CFB, BF, BFD
Similar products CFB, BF, BFD, GBG, PBF2, Complement Factor B, C3/C5 Convertase, Glycine-Rich Beta Glycoprotein, Properdin Factor B
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Synonym
Complement Factor B, C3/C5 Convertase, Glycine-Rich Beta Glycoprotein, GBG, PBF2, Properdin Factor B, CFB, BF, BFD
Storage
< -20CC
Protein Construction
Recombinant Human Complement Factor B is produced by our Mammalian expression system and the target gene encoding Thr26-Leu764 is expressed with a 6His tag at the C-terminus.
Sequence
Thr 26-Leu764
Fusion tag
C-6His
Accession
P00751
Shipping
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20CC.
Purity
> 95 % as determined by reducing SDS-PAGE.
Endotoxin
< 1.0 EU per ug as determined by the LAL method.
Stability and Storage
Store at < -20CC, stable for 6 months. Please minimize freeze-thaw cycles.
Mol Mass
84.1 kDa
AP Mol Mass
90 kDa
Formulation
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.
Reconstitution
Please refer to the printed manual for detailed information.
Background
Complement Factor B (CFB) belongs to the peptidase S1 family of enzymes. It is expressed by hepatocytes and macrophages and localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. CFB which is a component of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50ug
Lieferbar: In stock
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