ArtNr |
ELS-PKSH031568-20ug |
Hersteller |
Elabscience
|
Menge |
20ug |
Kategorie |
|
Typ |
Proteins |
Specific against |
Human |
Host |
E.coli |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
CA5,CA5AD,CA5D,Carbonic Anhydrase VA,CAV,CAVA,GS1-21A4.1 |
Similar products |
CA5, CAV, CAVA, Carbonic Anhydrase VA, CA5AD, CA5D, GS1-21A4.1 |
Lieferbar |
|
Synonym |
CA5, CA5AD, CA5D, Carbonic Anhydrase VA, CAV, CAVA, GS1-21A4.1 |
Storage |
according to manual |
Activity |
Measured by its esterase activity. The specific activity is >500 pmoles/min/ug. |
Protein Construction |
A DNA sequence encoding the mature form of human CA5A (NP_001730.1) (Ala 40-Ser 305) was fused with an Met at N-terminus and a polyhistide tag at the C-terminus. |
Sequence |
Ala 40-Ser 305 |
Fusion tag |
C-His |
Accession |
NP_001730.1 |
Shipping |
This product is provided as lyophilized powder which is shipped with ice packs. |
Purity |
> 96 % as determined by reducing SDS-PAGE. |
Endotoxin |
Please contact us for more information. |
Stability and Storage |
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80CC. Reconstituted protein solution can be stored at 4-8C for 2-7 days. Aliquots of reconstituted samples are stable at < -20C for 3 months. |
Mol Mass |
31.6 kDa |
AP Mol Mass |
33 kDa |
Formulation |
Lyophilized from sterile 50mM NaAc, 50mM NaCl, 0.05% Brij 35, pH 5.0 |
Reconstitution |
Please refer to the printed manual for detailed information. |
Background |
Carbonic anhydrase 5A, mitochondrial, also known as Carbonate dehydratase VA, Carbonic anhydrase VA, CA-VA and CA5A, is a member of the alpha-carbonic anhydrase family. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA5A / CA-VA is activated by histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. It is inhibited by coumarins, sulfonamide derivatives such as acetazolamide and Foscarnet (phosphonoformate trisodium salt). |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.