ArtNr |
ELS-PKSH031132-20ug |
Hersteller |
Elabscience
|
Menge |
20ug |
Kategorie |
|
Typ |
Proteins |
Specific against |
Human |
Host |
Baculovirus |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
C4ST,C4ST-1,C4ST1,HSA269537 |
Similar products |
C4ST, C4ST-1, C4ST1, HSA269537 |
Lieferbar |
|
Synonym |
C4ST, C4ST-1, C4ST1, HSA269537 |
Storage |
according to manual |
Protein Construction |
A DNA sequence encoding the human CHST11 (Q9NPF2-2) (Met36-Glu347) was expressed with a C-terminal polyhistidine tag. |
Sequence |
Met36-Glu347 |
Fusion tag |
C-His |
Accession |
Q9NPF2-2 |
Shipping |
This product is provided as lyophilized powder which is shipped with ice packs. |
Purity |
> 95 % as determined by reducing SDS-PAGE. |
Endotoxin |
< 1.0 EU per ug as determined by the LAL method. |
Stability and Storage |
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80CC. Reconstituted protein solution can be stored at 4-8C for 2-7 days. Aliquots of reconstituted samples are stable at < -20C for 3 months. |
Mol Mass |
38.4 kDa |
AP Mol Mass |
43 kDa |
Formulation |
Lyophilized from sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 7.4 |
Reconstitution |
Please refer to the printed manual for detailed information. |
Background |
CHST11, also known as C4ST-1, belongs to the sulfotransferase 2 family. CHST11 localizes to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving CHST11 gene and IgH, t(12; 14)(q23; q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. |
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