ArtNr |
ELS-PKSH030741-20ug |
Hersteller |
Elabscience
|
Menge |
20 ug |
Quantity options |
10 ug
20 ug
50 ug
|
Kategorie |
|
Typ |
Proteins |
Format |
Lyophilized Powder |
Specific against |
Human (Homo sapiens) |
Host |
HEK293 cells |
Konjugat/Tag |
HIS |
Purity |
> 97 % as determined by reducing SDS-PAGE. |
Sequence |
Met 1-Ala 388 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
FLJ58952, FLJ77962, PGA3, PGA4, PGA5 |
Similar products |
PGA3, PGA4, PGA5, FLJ58952, FLJ77962 |
Versandbedingung |
Gekühlt |
Lieferbar |
|
Manufacturer - Applications |
Enzyme |
Manufacturer - Category |
Recombinant Proteins / Others |
Manufacturer - Conjugate / Tag |
C-His |
Shipping Temperature |
This product is provided as lyophilized powder which is shipped with ice packs. |
Storage Conditions |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Calculated Molecular Weight |
41.7 kDa |
Observed Molecular Weight |
45 kDa |
Research Areas |
Signal Transduction, Cell Biology, Metabolism |
Background |
PGA4 (Pepsinogen 4; group I); or Pepsinogen A; is a member of the peptidase A1 family. Pepsin is expressed as a pro-form zymogen; pepsinogen; whose primary structure has an additional 44 amino acids. Pepsin is stored as pepsinogen so it will only be released when needed; and does not digest the body's own proteins in the stomach's lining. Five types of zymogens of pepsins; gastric digestive proteinases; are known: pepsinogens A; B; and F; progastricsin; and prochymosin. There are two major groups of pepsinogen; namely pepsinogen A (PGA) and pepsinogen C (PGC) (or progastricsin); and each frequently has isozymogens. The PGA3; PGA4 and PGA5 genes encode identical human pepsinogen A enzymes. |
Endotoxin |
< 1.0 EU per μg of the protein as determined by the LAL method. |
Reconstitution |
Please refer to the printed manual for detailed information. |
Formulation |
Lyophilized from sterile PBS, pH 7.4 Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Activity |
Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2, AnaSpec, Catalog # 27114.The specific activity is > 10, 000 pmoles/min/μg. (Activation description: The enzyme achieves its activity under acidic pH) |