Recombinant Human STC2/Stanniocalcin 2 Protein (His Tag)

STC-2, STCRP

A DNA sequence encoding the human STC2 (O76061) (Met1-Arg302) was expressed with a C-terminal polyhistidine tag.

C-His

This product is provided as lyophilized powder which is shipped with ice packs.

< 1.0 EU per ug as determined by the LAL method.

32.1 kDa

Lyophilized from sterile PBS; pH 7.4

STC2 is a secreted; homodimeric glycoprotein which expressed in a wide variety of tissues. STC2 has an anti-hypocalcemic action on calcium and phosphate homeostasis. It may have autocrine or paracrine functions. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. STC2 has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. It may play a role in the regulation of renal and intestinal calcium and phosphate transport; cell metabolism; or cellular calcium/phosphate homeostasis.