ArtNr |
E-AB-F1011G-50 |
Hersteller |
Elabscience
|
Menge |
50Tests |
Kategorie |
|
Typ |
Antibody Monoclonal |
Applikationen |
FC |
Clon |
Mel14 |
Specific against |
Mouse |
Host |
Rat |
Isotype |
IgG2a kappa |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
L-selectin, Sell, CD62 antigen-like family member L, LAM-1, LECAM1, Lymph node homing receptor, Ly-22, CD62L, Lnhr, Ly22 |
Similar products |
CD62L, Sell, Lymph node homing receptor, LAM-1, LECAM1, Ly-22, L-selectin, CD62 antigen-like family member L, Lnhr, Ly22 |
Lieferbar |
|
Synonyms |
L-selectin, Sell, CD62 antigen-like family member L, LAM-1, LECAM1, Lymph node homing receptor, Ly-22, CD62L, Lnhr, Ly22 |
Swissprot |
P18337 |
Background |
CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and nave T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte "rolling" on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish nave, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1. |
Storage |
Store at 2ca.8C and protected from prolonged exposure to light. Do not freeze. |
Buffer |
PBS with 0.05% Proclin300, 1% BSA |
Conjugation |
PE/Cyanine5 |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.