FMR1 Polyclonal Antibody

FMR1

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

71kDa

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

WB 1:500-1:1000; IHC 1:50-1:200

Polyclonal

Polyclonal Antibodies