ArtNr |
E-AB-63843-120 |
Hersteller |
Elabscience
|
Menge |
120uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
FMR 1, Fmr1, Fmr1 gene, FMR1, FMRP, Fragile X mental retardation 1, Fragile X mental retardation 1 protein, Fragile X mental retardation protein 1, Fragile X mental retardation protein, fragile X mental retardation syndrome-related protein 1, fragile X me |
Similar products |
FMR1, Fmr1, Fragile X mental retardation protein 1, POF1, fxr1, POF, FMRP, FRAXA, MGC87458, FMR 1, Fragile X mental retardation 1, Fragile X mental retardation 1 protein, Protein FMR-1, Fmr1 gene, Fragile X mental retardation protein, fragile X mental retardation syndrome-related protein 1, fragile X mental retardation, autosomal homolog 1, Protein FMR1, wu:fb16f11, wu:fd18c10, zgc:66226 |
Lieferbar |
|
Research Areas |
Cancer, Epigenetics and Nuclear Signaling, Neuroscience |
Synonyms |
FMR 1, Fmr1, Fmr1 gene, FMR1, FMRP, Fragile X mental retardation 1, Fragile X mental retardation 1 protein, Fragile X mental retardation protein 1, Fragile X mental retardation protein, fragile X mental retardation syndrome-related protein 1, fragile X mental retardation, autosomal homolog 1, FRAXA, fxr1, MGC87458, POF, POF1, Protein FMR-1, Protein FMR1, wu:fb16f11, wu:fd18c10, zgc:66226 |
Swissprot |
Q06787 |
Background |
The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
A synthetic peptide of human FMR1 |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:1000 |
Conjugation |
Unconjugated |
Calculated MW |
58kDa/61kDa/66kDa/68kDa/69kDa/70kDa/71kDa |
Observed MW |
75kDa |
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