ArtNr |
E-AB-70286-120 |
Hersteller |
Elabscience
|
Menge |
120uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Cdc 2, Cdc2, CDC28A, CDK 1, CDK1, CDK1, CDKN1, CELL CYCLE CONTROLLER CDC2, Cell division control protein 2, Cell division control protein 2 homolog, Cell division cycle 2 G1 to S and G2 to M, Cell division protein kinase 1, Cell Divsion Cycle 2 Protein, C |
Similar products |
CDK1, CDKN1, Cdc2, Cyclin-dependent kinase 1, Cell division control protein 2 homolog, Cell division protein kinase 1, p34 protein kinase, CDC28A, P34CDC2, Cdc 2, CDK 1, Cell division control protein 2, Cell division cycle 2 G1 to S and G2 to M, Cell Divsion Cycle 2 Protein, DKFZp686L20222, MGC111195, CELL CYCLE CONTROLLER CDC2, Cyclin Dependent Kinase 1, p34 Cdk1 |
Lieferbar |
|
Research Areas |
Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Neuroscience |
Synonyms |
Cdc 2, Cdc2, CDC28A, CDK 1, CDK1, CDK1, CDKN1, CELL CYCLE CONTROLLER CDC2, Cell division control protein 2, Cell division control protein 2 homolog, Cell division cycle 2 G1 to S and G2 to M, Cell division protein kinase 1, Cell Divsion Cycle 2 Protein, Cyclin Dependent Kinase 1, Cyclin-dependent kinase 1, DKFZp686L20222, MGC111195, p34 Cdk1, p34 protein kinase, P34CDC2 |
Swissprot |
P06493, P11440, P39951 |
Background |
CDK1, also named as CDC2, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family and CDC2/CDKX subfamily.CDC2 plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. CDC2 is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. It is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II. Mitotic cyclins stably associate with CDC2 and function as regulatory subunits. The antibody is specific to the 2 isoforms of CDC2. |
Concentration |
2.5 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
KLH conjugated Synthetic peptide corresponding to mouse CDK1 |
Buffer |
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4 |
Purification Method |
Affinity purification |
Dilution |
WB 1:500-1:2000 |
Conjugation |
Unconjugated |
Calculated MW |
34kDa |
Observed MW |
34kDa |
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