ArtNr |
E-AB-64388-60 |
Hersteller |
Elabscience
|
Menge |
60uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
ATP6M, ATP6V1D, V-ATPase 28 kDa accessory protein , V-ATPase subunit D, V-type proton ATPase subunit D, Vacuolar ATP synthase subunit D, Vacuolar proton pump subunit D, VATD, VMA8 |
Similar products |
ATP6V1D, VMA8, ATP6M, VATD, V-ATPase subunit D, V-type proton ATPase subunit D, Vacuolar proton pump subunit D, V-ATPase 28 kDa accessory protein, Vacuolar ATP synthase subunit D |
Lieferbar |
|
Research Areas |
Cancer, Metabolism, Signal Transduction |
Synonyms |
ATP6M, ATP6V1D, V-ATPase 28 kDa accessory protein , V-ATPase subunit D, V-type proton ATPase subunit D, Vacuolar ATP synthase subunit D, Vacuolar proton pump subunit D, VATD, VMA8 |
Swissprot |
Q9Y5K8 |
Background |
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human ATP6V1D |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 |
Conjugation |
Unconjugated |
Calculated MW |
28kDa |
Observed MW |
35kDa |
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