ArtNr |
E-AB-63953-200 |
Hersteller |
Elabscience
|
Menge |
200uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
PFKFB2, 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 2, 6PF-2-K/Fru-2, 6-P2ase 2, PFK/FBPase 2, 6PF-2-K/Fru-2, 6-P2ase heart-type isozyme |
Similar products |
6-phosphofructo-2-kinase/fructose-2, 6PF-2-K/Fru-2, PFKFB2, 6-bisphosphatase 2, 6-P2ase heart-type isozyme, 6-P2ase 2, PFK/FBPase 2 |
Lieferbar |
|
Synonyms |
PFKFB2, 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 2, 6PF-2-K/Fru-2, 6-P2ase 2, PFK/FBPase 2, 6PF-2-K/Fru-2, 6-P2ase heart-type isozyme |
Swissprot |
O60825 |
Background |
The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2, 6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2, 6-bisphosphate, and a fructose-2, 6-biphosphatase activity that catalyzes the degradation of fructose-2, 6-bisphosphate. This protein regulates fructose-2, 6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2, 6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human PFKFB2 |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 |
Conjugation |
Unconjugated |
Calculated MW |
54kDa/58kDa |
Observed MW |
54kDa |
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