Alias |
Alpha L fucosidase 2, Alpha L fucosidase fucohydrolase 2, Alpha-L-fucosidase 2, Alpha-L-fucoside fucohydrolase 2, dJ20N2.5, FUCA 2, FUCA2, FUCO2, FUCO2, Fucosidase alpha L 2 plasma, Fucosidase, alpha-L, plasma, MGC1314, Plasma alpha L fucosidase, Plasma a |
Synonyms |
Alpha L fucosidase 2, Alpha L fucosidase fucohydrolase 2, Alpha-L-fucosidase 2, Alpha-L-fucoside fucohydrolase 2, dJ20N2.5, FUCA 2, FUCA2, FUCO2, FUCO2, Fucosidase alpha L 2 plasma, Fucosidase, alpha-L, plasma, MGC1314, Plasma alpha L fucosidase, Plasma alpha-L-fucosidase, RP1 20N2.5 |
Background |
This gene encodes a plasma alpha-L-fucosidase, which represents 10-20% of the total cellular fucosidase activity. The protein is a member of the glycosyl hydrolase 29 family, and catalyzes the hydrolysis of the alpha-1, 6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. This enzyme is essential for Helicobacter pylori adhesion to human gastric cancer cells. |