USP8 Polyclonal Antibody

Deubiquitinating enzyme 8, FLJ34456, hUBPy, HumORF8, KIAA0055, MGC129718, SPG59, Ubiquitin carboxyl-terminal hydrolase 8, Ubiquitin isopeptidase Y, ubiquitin specific peptidase 8, Ubiquitin thioesterase 8, Ubiquitin-specific-processing protease 8, UBP8, UBPY, Usp8

This gene encodes a protein that belongs to the ubiquitin-specific processing protease family of proteins. The encoded protein is thought to regulate the morphology of the endosome by ubiquitination of proteins on this organelle and is involved in cargo sorting and membrane trafficking at the early endosome stage. This protein is required for the cell to enter the S phase of the cell cycle and also functions as a positive regulator in the Hedgehog signaling pathway in development. Pseudogenes of this gene are present on chromosomes 2 and 6. Alternate splicing results in multiple transcript variants.

Store at -20C. Avoid freeze / thaw cycles.

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

WB 1:500 - 1:2000 IF 1:50 - 1:200

115kDa/127kDa