ArtNr |
E-AB-61036-60 |
Hersteller |
Elabscience
|
Menge |
60uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
FGG, FIBG, Fibrinogen gamma chain, Fibrinogen gamma polypeptide, fibrinogen gamma-b chain |
Similar products |
FGG, Fibrinogen gamma chain, FIBG, Fibrinogen gamma polypeptide, fibrinogen gamma-b chain |
Lieferbar |
|
Research Areas |
Cancer, Cardiovascular |
Synonyms |
FGG, FIBG, Fibrinogen gamma chain, Fibrinogen gamma polypeptide, fibrinogen gamma-b chain |
Swissprot |
P02679 |
Background |
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human FGG |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 |
Conjugation |
Unconjugated |
Calculated MW |
49kDa/51kDa |
Observed MW |
53kDa |
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