KCNA1 Polyclonal Antibody

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

56kDa

This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

WB 1:500-1:2000; IHC 1:15-1:50

KCNA1

Synthetic peptide of human KCNA1