ArtNr |
E-AB-12444-200 |
Hersteller |
Elabscience
|
Menge |
200uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IHC, ELISA |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
BB2, Bombesin BB2 receptor, bombesin receptor 2, Gastrin Releasing Peptide Receptor, Gastrin-releasing peptide receptor, GRP preferring bombesin receptor, GRP R, GRP-preferring bombesin receptor, GRP-R, Grp/bombesin receptor, Grpr, GRPR |
Similar products |
GRPR, GRP-preferring bombesin receptor, BB2, Gastrin-releasing peptide receptor, GRP-R, Bombesin BB2 receptor, Grp/bombesin receptor, GRP preferring bombesin receptor, bombesin receptor 2, Gastrin Releasing Peptide Receptor, GRP R, Grpr |
Lieferbar |
|
Research Areas |
Cancer, Neuroscience, Signal Transduction |
Synonyms |
BB2, Bombesin BB2 receptor, bombesin receptor 2, Gastrin Releasing Peptide Receptor, Gastrin-releasing peptide receptor, GRP preferring bombesin receptor, GRP R, GRP-preferring bombesin receptor, GRP-R, Grp/bombesin receptor, Grpr, GRPR |
Swissprot |
P30550 |
Background |
Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. |
Concentration |
1.1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Synthetic peptide of human GRPR |
Buffer |
PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method |
Affinity purification |
Dilution |
WB 1:200-1:1000, IHC 1:50-1:200 |
Conjugation |
Unconjugated |
Calculated MW |
43kDa |
Gene Accession |
NP_005305 |
Santa Cruz # |
sc-26835, sc-26836, sc-32903 |
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