ArtNr |
E-AB-10990-60 |
Hersteller |
Elabscience
|
Menge |
60uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
IHC, ELISA |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
alternative ataxin1, Ataxin-1, ATX1, ATX1, Atxn1, D6S504E, OTTHUMP00000016065, SCA1, Spinocerebellar ataxia type 1 protein |
Similar products |
Ataxin-1, ATX1, D6S504E, SCA1, OTTHUMP00000016065, Atxn1, Spinocerebellar ataxia type 1 protein, alternative ataxin1 |
Lieferbar |
|
Research Areas |
Epigenetics and Nuclear Signaling, Neuroscience |
Synonyms |
alternative ataxin1, Ataxin-1, ATX1, ATX1, Atxn1, D6S504E, OTTHUMP00000016065, SCA1, Spinocerebellar ataxia type 1 protein |
Swissprot |
P54253 |
Background |
The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. |
Concentration |
0.4 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human ATXN1 |
Buffer |
PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method |
Affinity purification |
Dilution |
IHC 1:50-1:200 |
Conjugation |
Unconjugated |
Gene Accession |
BC117125 |
Santa Cruz # |
sc-8766, sc-12526, sc-12527 |
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