ArtNr |
E-AB-70121-200 |
Hersteller |
Elabscience
|
Menge |
200uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
IHC |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
NR3C3, Nuclear receptor subfamily 3 group C member 3, PGR, PR, PRA, PRB, PRGR, Progesterone receptor, Progestin receptor form A, Progestin receptor form B |
Similar products |
PR, PGR, NR3C3, Progesterone receptor, Nuclear receptor subfamily 3 group C member 3, PRB, PRA, Progestin receptor form A, Progestin receptor form B, Progestin receptor form A, PRGR |
Lieferbar |
|
Research Areas |
Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Signal Transduction |
Synonyms |
NR3C3, Nuclear receptor subfamily 3 group C member 3, PGR, PR, PRA, PRB, PRGR, Progesterone receptor, Progestin receptor form A, Progestin receptor form B |
Swissprot |
P06401, Q00175, Q63449 |
Background |
PGR, also named as NR3C3 and PR, belongs to the nuclear hormone receptor family and NR3 subfamily. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. The ER and PR status has been used as a predictor of breast carcinoma responsiveness to endocrine therapy and as a prognostic indicator for early recurrence. |
Concentration |
1.32 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Progesterone receptor |
Buffer |
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4 |
Purification Method |
Affinity purification |
Dilution |
IHC 1:200-1:800 |
Conjugation |
Unconjugated |
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