ArtNr |
E-AB-65386-120 |
Hersteller |
Elabscience
|
Menge |
120uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
RING finger protein 88, RNF88, TRIM5, TRIM5, TRIM5alpha, Tripartite motif containing 5, tripartite motif protein TRIM5, Tripartite motif-containing protein 5 |
Similar products |
TRIM5, RNF88, Tripartite motif-containing protein 5, RING finger protein 88, TRIM5alpha, tripartite motif protein TRIM5, Tripartite motif containing 5 |
Lieferbar |
|
Research Areas |
Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Immunology |
Synonyms |
RING finger protein 88, RNF88, TRIM5, TRIM5, TRIM5alpha, Tripartite motif containing 5, tripartite motif protein TRIM5, Tripartite motif-containing protein 5 |
Swissprot |
Q9C035 |
Background |
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
A synthetic peptide of human TRIM5 |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 |
Conjugation |
Unconjugated |
Calculated MW |
29kDa/31kDa/37kDa/40kDa/46kDa/56kDa |
Observed MW |
50kDa |
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