ArtNr |
E-AB-61154-120 |
Hersteller |
Elabscience
|
Menge |
120uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Uncoupling Protein 1, Uncoupling Protein 1 (Mitochondrial, Proton Carrier), Solute Carrier Family 25 Member 7, Thermogenin, SLC25A7, UCP, Mitochondrial Brown Fat Uncoupling Protein 1, UCP 1. |
Similar products |
SLC25A7, UCP, Thermogenin, Uncoupling Protein 1, Uncoupling Protein 1 (Mitochondrial, Proton Carrier), Solute Carrier Family 25 Member 7, Mitochondrial Brown Fat Uncoupling Protein 1, UCP 1. |
Lieferbar |
|
Research Areas |
Cancer, Metabolism, Signal Transduction |
Synonyms |
Uncoupling Protein 1, Uncoupling Protein 1 (Mitochondrial, Proton Carrier), Solute Carrier Family 25 Member 7, Thermogenin, SLC25A7, UCP, Mitochondrial Brown Fat Uncoupling Protein 1, UCP 1. |
Swissprot |
P25874 |
Background |
Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human UCP1 |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 |
Conjugation |
Unconjugated |
Calculated MW |
33kDa |
Observed MW |
32kDa |
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