ArtNr |
E-AB-60981-60 |
Hersteller |
Elabscience
|
Menge |
60uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
CPHD6, Homeobox protein OTX2, MCOPS 5, MCOPS5, MGC45000, Orthodenticle 2, Orthodenticle homeobox 2, Orthodenticle homolog 2 (Drosophila), Orthodenticle homolog 2, Orthodenticle2, Otx 2, otx2, OTX2 |
Similar products |
OTX2, otx2, MCOPS5, MGC45000, Homeobox protein OTX2, MCOPS 5, Orthodenticle 2, Orthodenticle homeobox 2, Orthodenticle homolog 2, Orthodenticle2, Otx 2, CPHD6, Orthodenticle homolog 2 (Drosophila) |
Lieferbar |
|
Research Areas |
Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Neuroscience, Stem Cells |
Synonyms |
CPHD6, Homeobox protein OTX2, MCOPS 5, MCOPS5, MGC45000, Orthodenticle 2, Orthodenticle homeobox 2, Orthodenticle homolog 2 (Drosophila), Orthodenticle homolog 2, Orthodenticle2, Otx 2, otx2, OTX2 |
Swissprot |
P32243 |
Background |
This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human OTX2 |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 |
Conjugation |
Unconjugated |
Calculated MW |
31kDa/32kDa |
Observed MW |
37kDa |
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