ArtNr |
E-AB-60902-60 |
Hersteller |
Elabscience
|
Menge |
60uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IF, IHC |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
dystonia 11, myoclonic, DYT11, Epsilon sarcoglycan, Epsilon SG, Epsilon-sarcoglycan, Epsilon-SG, ESG, sarcoglycan, epsilon, sgcE, SGCE |
Similar products |
SGCE, sgcE, epsilon, sarcoglycan, DYT11, ESG, dystonia 11, myoclonic, Epsilon-sarcoglycan, Epsilon sarcoglycan, Epsilon SG, Epsilon-SG |
Lieferbar |
|
Research Areas |
Developmental Biology, Signal Transduction |
Synonyms |
dystonia 11, myoclonic, DYT11, Epsilon sarcoglycan, Epsilon SG, Epsilon-sarcoglycan, Epsilon-SG, ESG, sarcoglycan, epsilon, sgcE, SGCE |
Swissprot |
O43556 |
Background |
This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A pseudogene associated with this gene is located on chromosome 2. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human SGCE |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
Conjugation |
Unconjugated |
Calculated MW |
49kDa/51kDa/52kDa |
Observed MW |
55kDa |
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