ArtNr |
E-AB-60137-120 |
Hersteller |
Elabscience
|
Menge |
120uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IF, IP |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
ARB1, ARR1, ARRB1, ARRB1, Arrestin 2, Arrestin beta 1, Arrestin beta-1, Beta-arrestin-1 |
Similar products |
ARRB1, ARR1, Beta-arrestin-1, Arrestin beta-1, ARB1, Arrestin 2, Arrestin beta 1 |
Lieferbar |
|
Research Areas |
Cancer, Neuroscience, Signal Transduction |
Synonyms |
ARB1, ARR1, ARRB1, ARRB1, Arrestin 2, Arrestin beta 1, Arrestin beta-1, Beta-arrestin-1 |
Swissprot |
P49407 |
Background |
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human ARRB1 |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 IF 1:20 - 1:100 IP 1:50 - 1:100 |
Conjugation |
Unconjugated |
Calculated MW |
46kDa/47kDa |
Observed MW |
56kDa |
Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.
Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.