FBXL4 Polyclonal Antibody

F box and leucine rich repeat protein 4, F box protein FBL4/FBL5, F box/LRR repeat protein 4, F-box and leucine-rich repeat protein 4, F-box protein FBL 4, F-box protein FBL4/FBL5, F-box/LRR-repeat protein 4, FBL 4, FBL 5, FBL4, FBL5, Fbxl4, FBXL4, MTDPS13

This gene encodes a member of the F-box protein family, which are characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes, called SCF complexes, which function in phosphorylation-dependent ubiquitination. The F-box domain mediates protein-protein interactions and binds directly to S-phase kinase-associated protein 1. In addition to an F-box domain, the encoded protein contains at least 9 tandem leucine-rich repeats. The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A. Alternative splicing results in multiple transcript variants.

Store at -20C. Avoid freeze / thaw cycles.

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

IHC 1:30-1:150, ELISA 1:5000-1:10000

NP036292