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MECOM Polyclonal Antibody

MECOM Polyclonal Antibody

ArtNr	E-AB-19826-120
Hersteller	Elabscience
Menge	120uL
Kategorie	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Development Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Melanoma Sarcoma Myelofibrosis Immunohistochemistry ELISA Primary Antibodies By Organ Breast Cancer
Typ	Antibody Polyclonal
Applikationen	IHC, ELISA
Specific against	Human, Mouse
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Ecotropic Virus Integration Site 1 Protein Homolog, MDS1 And EVI1 Complex Locus Protein, PR Domain 3, EVI1, MDS1, MDS1 And EVI1 Complex Locus Protein EVI1, MDS1 And EVI1 Complex Locus Protein MDS1, Ecotropic Viral Integration Site 1, Myelodysplasia Syndro
Similar products	MDS1, EVI1, AML1-EVI-1, MDS1-EVI1, PRDM3, Ecotropic Virus Integration Site 1 Protein Homolog, PR Domain 3, MDS1 And EVI1 Complex Locus Protein EVI1, MDS1 And EVI1 Complex Locus Protein MDS1, Ecotropic Viral Integration Site 1, Myelodysplasia Syndrome 1 Protein, Zinc Finger Protein Evi1, Oncogene EVI1, RUSAT2, KMT8E, MDS1 And EVI1 Complex Locus Protein
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Research Areas	Cancer, Epigenetics and Nuclear Signaling
Synonyms	Ecotropic Virus Integration Site 1 Protein Homolog, MDS1 And EVI1 Complex Locus Protein, PR Domain 3, EVI1, MDS1, MDS1 And EVI1 Complex Locus Protein EVI1, MDS1 And EVI1 Complex Locus Protein MDS1, Ecotropic Viral Integration Site 1, Myelodysplasia Syndrome 1 Protein, Zinc Finger Protein Evi1, Oncogene EVI1, AML1-EVI-1, MDS1-EVI1, RUSAT2, KMT8E, PRDM3
Swissprot	Q03112
Background	The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
Concentration	1.68 mg/mL
Storage	Store at -20C. Avoid freeze / thaw cycles.
Immunogen	Synthetic peptide of human MECOM
Buffer	PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method	Antigen affinity purification
Dilution	IHC 1:40-1:200, ELISA 1:5000-1:10000
Conjugation	Unconjugated
Gene Accession	NP005232

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 120uL

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Lieferung vsl. bis 06.09.2024

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