ArtNr |
E-AB-15758-60 |
Hersteller |
Elabscience
|
Menge |
60uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
IHC, ELISA |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
BMND1, EVR1, EVR4, HBM, Low density lipoprotein receptor related protein 5, Low density lipoprotein receptor related protein 7, Low-density lipoprotein receptor-related protein 5, LR3, LRP-5, Lrp5, LRP5, LRP7, OPPG, OPS, OPTA1, Osteoporosis pseudoglioma s |
Similar products |
LRP5, LR3, LRP7, Low-density lipoprotein receptor-related protein 5, HBM, Lrp5, EVR1, BMND1, EVR4, OPPG, OPS, OPTA1, VBCH2, LRP-5, Low density lipoprotein receptor related protein 5, Low density lipoprotein receptor related protein 7, Osteoporosis pseudoglioma syndrome |
Lieferbar |
|
Research Areas |
Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction, Stem Cells |
Synonyms |
BMND1, EVR1, EVR4, HBM, Low density lipoprotein receptor related protein 5, Low density lipoprotein receptor related protein 7, Low-density lipoprotein receptor-related protein 5, LR3, LRP-5, Lrp5, LRP5, LRP7, OPPG, OPS, OPTA1, Osteoporosis pseudoglioma syndrome, VBCH2 |
Swissprot |
O75197 |
Background |
This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. |
Concentration |
1.4 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Synthetic peptide of human LRP5 |
Buffer |
PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method |
Affinity purification |
Dilution |
IHC 1:100-1:300 |
Conjugation |
Unconjugated |
Gene Accession |
NP_002326 |
Santa Cruz # |
sc-21389, sc-21390 |
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