ArtNr |
E-AB-15735-120 |
Hersteller |
Elabscience
|
Menge |
120uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IHC, ELISA |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
c Jun kinase 2, C Jun N terminal kinase 2, c-Jun N-terminal kinase 2, JNK 55, JNK-55, JNK2 alpha, JNK2, JNK2 beta, JNK2A, JNK2alpha, JNK2B, JNK2BETA, Jun kinase, MAP kinase 9, MAPK 9, Mapk9, Mitogen activated protein kinase 9, Mitogen-activated protein ki |
Similar products |
JNK2, Mapk9, Mitogen-activated protein kinase 9, Stress-activated protein kinase JNK2, c-Jun N-terminal kinase 2, 9, mitogen-activated, JNK-55, JNK2A, JNK2B, JNK2BETA, PRKM9, SAPK, p54aSAPK, Jun kinase, MAP kinase 9, MK09, SAPK1a, MAPK 9, C Jun N terminal kinase 2, JNK 55, JNK2 alpha, JNK2 beta, JNK2alpha, Mitogen activated protein kinase 9, SAPK alpha, Protein kinase, Stress activated protein kinase 1a, c Jun kinase 2, P54a |
Lieferbar |
|
Research Areas |
Cancer, Cell Biology, Metabolism, Immunology, Signal Transduction |
Synonyms |
c Jun kinase 2, C Jun N terminal kinase 2, c-Jun N-terminal kinase 2, JNK 55, JNK-55, JNK2 alpha, JNK2, JNK2 beta, JNK2A, JNK2alpha, JNK2B, JNK2BETA, Jun kinase, MAP kinase 9, MAPK 9, Mapk9, Mitogen activated protein kinase 9, Mitogen-activated protein kinase 9, MK09, P54a, p54aSAPK, PRKM9, Protein kinase, mitogen-activated, 9, SAPK alpha, SAPK, SAPK1a, Stress activated protein kinase 1a, Stress-activated protein kinase JNK2 |
Swissprot |
P45984 |
Background |
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.JNK2 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it. |
Concentration |
0.4 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Synthetic peptide of human MAPK9 |
Buffer |
PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method |
Affinity purification |
Dilution |
WB 1:500-1:2000, IHC 1:25-1:100 |
Conjugation |
Unconjugated |
Calculated MW |
48kDa |
Observed MW |
Refer to figures |
Gene Accession |
NP_620707 |
Santa Cruz # |
sc-46013, sc-46011, sc-827, sc-572 |
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