ArtNr |
E-AB-15724-60 |
Hersteller |
Elabscience
|
Menge |
60 uL |
Quantity options |
120 uL
20 uL
200 uL
60 uL
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IHC, ELISA |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus) |
Host |
Rabbit |
Isotype |
IgG |
Konjugat/Tag |
Unconjugated |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
IASPP, inhibitor of apoptosis stimulating protein of p53, Inhibitor of ASPP protein, NFkB interacting protein 1, NKIP1, PPP1R13B-like protein, PPP1R13L, Protein iASPP, protein phosphatase 1 regulatory (inhibitor) subunit 13 like, RAI, RelA-associated inhibitor |
Similar products |
IASPP, PPP1R13L, NKIP1, RAI, NFkB interacting protein 1, RelA-associated inhibitor, inhibitor of apoptosis stimulating protein of p53, Inhibitor of ASPP protein, PPP1R13B-like protein, Protein iASPP, protein phosphatase 1 regulatory (inhibitor) subunit 13 like |
Versandbedingung |
Gekühlt |
Lieferbar |
|
Manufacturer - Category |
Primary Antibodies |
Shipping Temperature |
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Storage Conditions |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Calculated Molecular Weight |
89kDa |
Research Areas |
Cancer, Cell Biology, Epigenetics and Nuclear Signaling |
Background |
RelA-associated inhibitor is a protein that in humans is encoded by the PPP1R13L gene. Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. Interacts with RELA NF-kappa-B subunit and with SP1 via its C-terminus part. Interacts with p53/TP53, TP63 and TP73. |
Concentration |
0.6 mg/mL |
Buffer |
PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method |
Affinity purification |
Recommended Dilution |
WB 1:500-1:2000; IHC 1:50-1:200 |
Santa Cruz # |
sc-74941, sc-74942, sc-133686 |
Abbreviation |
PPP1R13L |
Clonality |
Polyclonal |
Immunogen |
Synthetic peptide of human PPP1R13L |
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