ArtNr |
E-AB-31644-60 |
Hersteller |
Elabscience
|
Menge |
60uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, ELISA, IHC-P |
Specific against |
Human, Mouse, Rat, Monkey |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
D10Wsu179e, HD 2, HD2, HDAC 2, Hdac2, HDAC2, Histone deacetylase 2 (HD2), Histone deacetylase 2, OTTHUMP00000017046, OTTHUMP00000227077, OTTHUMP00000227078, RPD3, transcriptional regulator homolog RPD3, YAF1, YY1 associated factor 1, YY1 transcription fac |
Similar products |
HDAC2, RPD3, HD2, YAF1, transcriptional regulator homolog RPD3, Hdac2, D10Wsu179e, HDAC 2, YY1 associated factor 1, YY1 transcription factor binding protein, Yy1bp, Histone deacetylase 2, HD 2, Histone deacetylase 2 (HD2), OTTHUMP00000017046, OTTHUMP00000227077, OTTHUMP00000227078 |
Lieferbar |
|
Research Areas |
Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Stem Cells |
Synonyms |
D10Wsu179e, HD 2, HD2, HDAC 2, Hdac2, HDAC2, Histone deacetylase 2 (HD2), Histone deacetylase 2, OTTHUMP00000017046, OTTHUMP00000227077, OTTHUMP00000227078, RPD3, transcriptional regulator homolog RPD3, YAF1, YY1 associated factor 1, YY1 transcription factor binding protein, Yy1bp |
Swissprot |
Q92769 |
Background |
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Synthesized peptide derived from human HDAC2 around the non-phosphorylation site of Ser394. |
Buffer |
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
Purification Method |
Affinity purification |
Dilution |
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000 |
Conjugation |
Unconjugated |
Calculated MW |
55kDa |
Observed MW |
55kDa |
Santa Cruz # |
sc-6296, sc-9959, sc-7899 |
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