ArtNr |
E-AB-F12110-50 |
Hersteller |
Elabscience
|
Menge |
50 ug |
Quantity options |
1 mg
100 mg
100 ug
25 mg
25 ug
50 ug
500 ug
5 mg
|
Kategorie |
|
Typ |
Antibody Monoclonal |
Applikationen |
FC, FA |
Clon |
R7-1 |
Specific against |
Human (Homo sapiens) |
Host |
Mouse |
Isotype |
IgG1 Kappa |
Konjugat/Tag |
Unconjugated |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Integrin alpha-L, LFA-1A, CD11A, ITGAL, |
Similar products |
ITGAL, CD11A, Integrin alpha-L, LFA-1A |
Versandbedingung |
Gekühlt |
Lieferbar |
|
Manufacturer - Category |
Flow Cytometry Antibodies |
Manufacturer - Isotype |
Mouse IgG1, κ |
Manufacturer - Conjugate / Tag |
None (AF/LE) |
Shipping Temperature |
Ice bag |
Storage Conditions |
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
Background |
CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50). |
Concentration |
≥1 mg/mL |
Buffer |
Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method. |
Abbreviation |
CD11a |
Clonality |
Monoclonal |
Usage |
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
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