ArtNr |
E-AB-62147-120 |
Hersteller |
Elabscience
|
Menge |
120uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IHC |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Cell proliferation-inducing gene 53 protein, E3 ubiquitin protein ligase Nedd4, E3 ubiquitin-protein ligase NEDD4, HECT-type E3 ubiquitin transferase NEDD4, KIAA0093, NEDD 4, NEDD-4, Nedd4, NEDD4, Neural precursor cell expressed developmentally down regul |
Similar products |
NEDD4, RPF1, E3 ubiquitin protein ligase, Nedd4, neural precursor cell expressed, KIAA0093, receptor-potentiating factor 1, E3 ubiquitin-protein ligase NEDD4, Cell proliferation-inducing gene 53 protein, Neural precursor cell expressed developmentally down-regulated protein 4, NEDD-4, PIG53, E3 ubiquitin protein ligase Nedd4, HECT-type E3 ubiquitin transferase NEDD4, NEDD 4, Neural precursor cell expressed developmentally down regulated 4, developmentally down-regulated 4 |
Lieferbar |
|
Research Areas |
Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Neuroscience |
Synonyms |
Cell proliferation-inducing gene 53 protein, E3 ubiquitin protein ligase Nedd4, E3 ubiquitin-protein ligase NEDD4, HECT-type E3 ubiquitin transferase NEDD4, KIAA0093, NEDD 4, NEDD-4, Nedd4, NEDD4, Neural precursor cell expressed developmentally down regulated 4, Neural precursor cell expressed developmentally down-regulated protein 4, neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase, PIG53, receptor-potentiating factor 1, RPF1 |
Swissprot |
P46934 |
Background |
This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human NEDD4 |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Conjugation |
Unconjugated |
Calculated MW |
104kDa/140kDa/147kDa/149kDa |
Observed MW |
120kDa |
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