ArtNr |
E-AB-61490-60 |
Hersteller |
Elabscience
|
Menge |
60uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IF |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
hN CoR, hNCoR, KIAA1047, N CoR, N Cor/SMRT corepressor Rip13, N CoR1, N-CoR, N-CoR1, NCOR 1, NCoR, Ncor1, NCOR1, Nuclear receptor co repressor 1, Nuclear receptor corepressor 1, Retinoid X receptor interacting protein 13, RIP13, Rxrip13, thyroid hormone a |
Similar products |
NCOR1, KIAA1047, Nuclear receptor corepressor 1, N-CoR, TRAC1, Ncor1, RIP13, Rxrip13, hN CoR, hNCoR, N CoR, N Cor/SMRT corepressor Rip13, N CoR1, NCOR 1, NCoR, Nuclear receptor co repressor 1, Retinoid X receptor interacting protein 13, thyroid hormone and retinoic acid receptor associated corepressor 1, TRAC 1, N-CoR1 |
Lieferbar |
|
Research Areas |
Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction |
Synonyms |
hN CoR, hNCoR, KIAA1047, N CoR, N Cor/SMRT corepressor Rip13, N CoR1, N-CoR, N-CoR1, NCOR 1, NCoR, Ncor1, NCOR1, Nuclear receptor co repressor 1, Nuclear receptor corepressor 1, Retinoid X receptor interacting protein 13, RIP13, Rxrip13, thyroid hormone and retinoic acid receptor associated corepressor 1, TRAC 1, TRAC1 |
Swissprot |
O75376 |
Background |
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human NCOR1 |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 IF 1:50 - 1:100 |
Conjugation |
Unconjugated |
Calculated MW |
103kDa/258kDa/270kDa |
Observed MW |
320kDa |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.