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BAG2 Polyclonal Antibody

BAG2 Polyclonal Antibody

ArtNr	E-AB-53382-60
Hersteller	Elabscience
Menge	60uL
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot ELISA Autophagy Primary Antibodies By Organ Colorectal Cancer Testicular & Prostate Cancer
Typ	Antibody Polyclonal
Applikationen	WB, IHC, ELISA
Specific against	Human
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	BAG 2, BAG family molecular chaperone regulator 2, BAG-2, BAG-family molecular chaperone regulator-2, Bag2, BAG2, BCL 2 associated athanogene 2, Bcl-2-associated athanogene 2, BCL2 associated athanogene 2, BCL2-associated athanogene 2, dJ417I1.2 (BAG fami
Similar products	BAG2, BAG family molecular chaperone regulator 2, Bcl-2-associated athanogene 2, Bag2, BAG-2, KIAA0576, MGC149462, dJ417I1.2, BAG-family molecular chaperone regulator-2, BAG 2, BCL 2 associated athanogene 2, BCL2 associated athanogene 2, BCL2-associated athanogene 2, dJ417I1.2 (BAG family molecular chaperone regulator 2), OTTHUMP00000016668
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Research Areas	Cell Biology, Signal Transduction, Cancer, Metabolism
Synonyms	BAG 2, BAG family molecular chaperone regulator 2, BAG-2, BAG-family molecular chaperone regulator-2, Bag2, BAG2, BCL 2 associated athanogene 2, Bcl-2-associated athanogene 2, BCL2 associated athanogene 2, BCL2-associated athanogene 2, dJ417I1.2 (BAG family molecular chaperone regulator 2), dJ417I1.2, KIAA0576, MGC149462, OTTHUMP00000016668
Swissprot	O95816
Background	BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Concentration	0.8 mg/mL
Storage	Store at -20C. Avoid freeze / thaw cycles.
Immunogen	Synthetic peptide of human BAG2
Buffer	PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method	Antigen affinity purification
Dilution	WB 1:500-1:2000, IHC 1:20-1:100, ELISA 1:5000-1:10000
Conjugation	Unconjugated
Calculated MW	24 kDa
Observed MW	Refer to figures
Gene Accession	NP004273

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 60uL

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Lieferung vsl. bis 11.10.2024

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