ArtNr |
E-AB-53132-20 |
Hersteller |
Elabscience
|
Menge |
20uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
IHC, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
C12orf52 , Chromosome 12 open reading frame 52 , RBPJ interacting and tubulin associated 1, RBPJ interacting and tubulin associated protein 1, RBPJ-interacting and tubulin-associated protein, RITA, RITA |
Similar products |
RITA, C12orf52, RBPJ-interacting and tubulin-associated protein, Chromosome 12 open reading frame 52, RBPJ interacting and tubulin associated 1, RBPJ interacting and tubulin associated protein 1 |
Lieferbar |
|
Research Areas |
Developmental biology, Neuroscience, Signal transduction, Stem cells |
Synonyms |
C12orf52 , Chromosome 12 open reading frame 52 , RBPJ interacting and tubulin associated 1, RBPJ interacting and tubulin associated protein 1, RBPJ-interacting and tubulin-associated protein, RITA, RITA |
Swissprot |
Q96K30 |
Background |
Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis. |
Concentration |
0.9 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Fusion protein of human RITA1 |
Buffer |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
Purification Method |
Antigen affinity purification |
Dilution |
IHC 1:50-1:200, ELISA 1:5000-1:10000 |
Conjugation |
Unconjugated |
Gene Accession |
BC022092 |
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