ArtNr |
E-AB-10547-60 |
Hersteller |
Elabscience
|
Menge |
60uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IHC, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
CD 87, CD87, CD87 antigen, MO 3, MO3, Monocyte activation antigen Mo3, Plasminogen activator receptor urokinase, Plasminogen activator urokinase receptor, PLAUR, U PAR, u plasminogen activator receptor, U-PAR, u-plasminogen activator receptor form 2, UPA |
Similar products |
PLAUR, MO3, UPAR, Urokinase plasminogen activator surface receptor, Monocyte activation antigen Mo3, CD87, U-PAR, uPAR, URKR, u-plasminogen activator receptor form 2, CD 87, CD87 antigen, MO 3, Plasminogen activator urokinase receptor, U PAR, u plasminogen activator receptor, UPA receptor, Urinary plasminogen activator receptor, Urokinase plasminogen activator receptor, Plasminogen activator receptor urokinase, urokinase-type plasminogen activator (uPA) receptor |
Lieferbar |
|
Research Areas |
Cancer, Cardiovascular, Immunology |
Synonyms |
CD 87, CD87, CD87 antigen, MO 3, MO3, Monocyte activation antigen Mo3, Plasminogen activator receptor urokinase, Plasminogen activator urokinase receptor, PLAUR, U PAR, u plasminogen activator receptor, U-PAR, u-plasminogen activator receptor form 2, UPA receptor, uPAR, UPAR, Urinary plasminogen activator receptor, URKR, Urokinase plasminogen activator receptor, Urokinase plasminogen activator surface receptor, urokinase-type plasminogen activator (uPA) receptor |
Swissprot |
Q03405 |
Background |
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. |
Concentration |
0.4 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human PLAUR |
Buffer |
PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method |
Affinity purification |
Dilution |
WB 1:500-1:2000, IHC 1:50-1:200 |
Conjugation |
Unconjugated |
Calculated MW |
37kDa |
Gene Accession |
BC002788 |
Santa Cruz # |
sc-9793, sc-9791, sc-13522, sc-10815 |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.