ArtNr |
CSB-YP891951HU-10 |
Hersteller |
Cusabio
|
Menge |
10ug |
Kategorie |
|
Typ |
Proteins Recombinant |
Format |
Liquid or Lyophilized powder |
Specific against |
other |
Host |
Yeast |
Purity |
Greater than 90% as determined by SDS-PAGE. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
COMPase |
Lieferbar |
|
Research Topic |
Cell Biology |
Uniprot ID |
Q9UKP4 |
Gene Names |
ADAMTS7 |
Organism |
Homo sapiens (Human) |
AA Sequence |
KWVETLVVADAKMVEYHGQPQVESYVLTIMNMVAG LFHDPSIGNPIHITIVRLVLLEDEEEDLKITHHAD NTLKSFCKWQKSINMKGDAHPLHHDTAILLTRKDL CAAMNRPCETLGLSHVAGMCQPHRSCSINEDTGLP LAFTVAHELGHSFGIQHDGSGNDCEPVGKRPFIMS PQLLYDAAPLTWSRCSRQYITRFLDRGWGLCLDDP PAKDIIDFPSVPPGVLYDVSHQCRLQYGAYSAFCE DMDNVCHTLWCSVGTTCHSKLDAAVDGTRCGENKW CLSGECVPVGFRPEAVDGGWSGWSAWSICSRSCGM GVQSAERQCTQPTPKYKGRYCVGERKRFRLCNLQA CP |
Expression Region |
242-593aa |
Sequence Info |
Partial |
Source |
Yeast |
Tag Info |
N-terminal 6xHis-tagged |
MW |
41.1 kDa |
Alternative Name(s) |
COMPase |
Relevance |
Metalloprotease that may play a role in the degradation of COMP. |
Reference |
"ADAMTS-7: a metalloproteinase that directly binds to and degrades cartilage oligomeric matrix protein."Liu C.-J., Kong W., Ilalov K., Yu S., Xu K., Prazak L., Fajardo M., Sehgal B., Di Cesare P.E.FASEB J. 20:988-990(2006) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage Buffer |
Tris-based buffer, 50% glycerol |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
Metalloprotease that may play a role in the degradation of COMP. |
Subcellular Location |
Secreted, extracellular space, extracellular matrix |
Tissue Specificity |
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Detected in meniscus, bone, tendon, cartilage, synovium, fat and ligaments. |
Tag Information |
N-terminal 6xHis-tagged |
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