ArtNr |
CSB-YP306050PAU-500 |
Hersteller |
Cusabio
|
Menge |
500 ug |
Quantity options |
1 mg
10 ug
100 ug
20 ug
200 ug
50 ug
500 ug
|
Kategorie |
|
Typ |
Proteins Recombinant |
Format |
Liquid or Lyophilized powder |
Specific against |
other |
Host |
Yeast |
Konjugat/Tag |
HIS |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Sequence |
FWGALAKGALKLIPSLFSSFSKKD |
Protein Familie |
Non-disulfide-bridged peptide (NDBP) superfamily, Medium-length antimicrobial peptide (group 3) family |
Citations |
Characterization of unique amphipathic antimicrobial peptides from venom of the scorpion Pandinus imperator.Corzo G., Escoubas P., Villegas E., Barnham K.J., He W., Norton R.S., Nakajima T.Biochem. J. 359:35-45(2001) |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Non-disulfide-bridged peptide 3.1; Short name:; NDBP-3.1; Non-disulfide-bridged peptide 4.1; Short name:; NDBP-4.1 |
Lieferbar |
|
Manufacturer - Conjugate / Tag |
N-terminal 6xHis-tagged |
Storage Conditions |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Molecular Weight |
4.6 kDa |
Buffer |
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
Relevance |
Disrupts cell membranes through formation of pores. Has strong antimicrobial activity against Gram-positive bacteria B.subtilis, S.epidermidis, E.faecalis and S.aureus. Is less active against Gram-negative bacteria P.aeruginosa and E.coli. Also increases efficacy of antibiotics (ampicillin, chloramphenicol, streptomycin, kanamycin, novobiocin) when tested against E.coli, probably by facilitating their incorporation into the bacteria. Possesses antifungal activity against C.albicans and hemolytic activity against human, sheep and pig erythrocytes. |
Expression Region |
1-24aa |
Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20C/-80C. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
Disrupts cell membranes through formation of pores. Has strong antimicrobial activity against Gram-positive bacteria B.subtilis, S.epidermidis, E.faecalis and S.aureus. Is less active against Gram-negative bacteria P.aeruginosa and E.coli. Also increases efficacy of antibiotics (ampicillin, chloramphenicol, streptomycin, kanamycin, novobiocin) when tested against E.coli, probably by facilitating their incorporation into the bacteria. Possesses antifungal activity against C.albicans and hemolytic activity against human, sheep and pig erythrocytes. |
Subcellular Location |
Secreted, Target cell membrane |
Tissue Specificity |
Expressed by the venom gland. |
Sequence Info |
Full Length |
Organism |
Pandinus imperator (Emperor scorpion) |
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