ArtNr |
CSB-YP004856HU-1 |
Hersteller |
Cusabio
|
Menge |
1mg |
Kategorie |
|
Typ |
Proteins Recombinant |
Format |
Liquid or Lyophilized powder |
Specific against |
other |
Host |
Yeast |
Purity |
Greater than 90% as determined by SDS-PAGE. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
CCT-beta |
Lieferbar |
|
Research Topic |
Signal Transduction |
Uniprot ID |
P78371 |
Gene Names |
CCT2 |
Organism |
Homo sapiens (Human) |
AA Sequence |
ASLSLAPVNIFKAGADEERAETARLTSFIGAIAIG DLVKSTLGPKGMDKILLSSGRDASLMVTNDGATIL KNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLA AELLREAESLIAKKIHPQTIIAGWREATKAAREAL LSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHK DHFTKLAVEAVLRLKGSGNLEAIHIIKKLGGSLAD SYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDT DKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVER ILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHAD FAGVERLALVTGGEIASTFDHPELVKLGSCKLIEE VMIGEDKLIHFSGVALGEACTIVLRGATQQILDEA ERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAV TQLANRTPGKEAVAMESYAKALRMLPTIIADNAGY DSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAIL GITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPR KRVPDHHPC |
Expression Region |
2-535aa |
Sequence Info |
Full Length of Mature Protein |
Source |
Yeast |
Tag Info |
N-terminal 6xHis-tagged |
MW |
59.4 kDa |
Alternative Name(s) |
CCT-beta |
Relevance |
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. |
Reference |
"Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT."Won K.-A., Schumacher R.J., Farr G.W., Horwich A.L., Reed S.I.Mol. Cell. Biol. 18:7584-7589(1998) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage Buffer |
Tris-based buffer, 50% glycerol |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. |
Subcellular Location |
Cytoplasm |
Protein Families |
TCP-1 chaperonin family |
Tag Information |
N-terminal 6xHis-tagged |
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