ArtNr |
CSB-YP003951HU-200 |
Hersteller |
Cusabio
|
Menge |
200ug |
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Host |
Yeast |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Proline-rich protein,Short name:,PRP |
Lieferbar |
|
Alternative Name(s) |
Proline-rich protein Short name: PRP |
AA Sequence |
NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLP GYVRSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGE LRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSR CEVQDRGVGWSHPLPQCEIVKCKPPPDIRNGRHSG EENFYAYGFSVTYSCDPRFSLLGHASISCTVENET IGVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYN YKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPA CEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVL RYRCHPGYKPTTDEPTTVICQKNLRWTPYQGCEAL CCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFS CHETSRFSAICQGDGTWSPRTPSCGDICNFPPKIA HGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSC SYSHWSAPAPQCKALCRKPELVNGRLSVDKDQYVE PENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKC EWETPEGCEQVLTGKRLMQCLPNPEDVKMALEVYK LSLEIEQLELQRDSARQSTLDKEL |
Research Topic |
Immunology |
Uniprot ID |
P04003 |
Gene Names |
C4BPA |
Tag Info |
N-terminal 6xHis-tagged |
Expression Region |
49-597aa |
MW of Fusion Proten |
63, 7 |
Sequence Info |
Full Length |
Relevance |
Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component. |
Reference |
"Molecular cloning and characterization of the cDNA coding for C4b-binding protein, a regulatory protein of the classical pathway of the human complement system."Chung L.P., Bentley D.R., Reid K.B.M.Biochem. J. 230:133-141(1985) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage Buffer |
Tris-based buffer, 50% glycerol |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Species |
Homo sapiens (Human) |
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