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Recombinant Mouse EF-hand domain-containing protein D2(Efhd2)

Recombinant Mouse EF-hand domain-containing protein D2(Efhd2)

ArtNr	CSB-EP861577MO-10
Hersteller	Cusabio
Menge	10ug
Quantity options	1mg 10ug 100ug 20ug 200ug 50ug 500ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Liquid or Lyophilized powder
Specific against	other
Host	E.coli
Purity	Greater than 90% as determined by SDS-PAGE.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Swiprosin-1
Lieferbar
Research Topic	Signal Transduction
Uniprot ID	Q9D8Y0
Gene Names	Efhd2
Organism	Mus musculus (Mouse)
AA Sequence	ATDELASKLSRRLQMEGEGGEATEQPGLNGAAAAA AAEAPDETAQALGSADDELSAKLLRRADLNQGIGE PQSPSRRVFNPYTEFKEFSRKQIKDMEKMFKQYDA GRDGFIDLMELKLMMEKLGAPQTHLGLKSMIQEVD EDFDSKLSFREFLLIFRKAAAGELQEDSGLQVLAR LSEIDVSTEGVKGAKNFFEAKVQAINVSSRFEEEI KAEQEERKKQAEEVKQRKAAFKELQSTFK
Expression Region	2-240aa
Sequence Info	Full Length of Mature Protein
Source	E.coli
Tag Info	N-terminal 6xHis-SUMO-tagged
MW	42.7 kDa
Alternative Name(s)	Swiprosin-1
Relevance	May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
Reference	"The transcriptional landscape of the mammalian genome."Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. Hayashizaki Y.Science 309:1559-1563(2005)
Purity	Greater than 90% as determined by SDS-PAGE.
Storage Buffer	Tris-based buffer, 50% glycerol
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function	May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
Subcellular Location	Membrane raft
Tissue Specificity	Detected in thymus, kidney, spleen, lung, liver and brain. Highest abundance in brain and lowest in kidney and thymus.
Tag Information	N-terminal 6xHis-SUMO-tagged

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