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Recombinant Human cytomegalovirus Viral interleukin-10 homolog(UL111A)

ArtNr CSB-EP517245HWW-200
Hersteller Cusabio
Menge 200ug
Kategorie
Typ Proteins Recombinant
Format Liquid or Lyophilized powder
Specific against other
Host E.coli
Purity Greater than 85% as determined by SDS-PAGE.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Lieferbar
AA Sequence
ATTTTIKNTKPQCRPEDYATRLQDLRVTFHRVKPT LQREDDYSVWLDGTVVKGCWGCSVMDWLLRRYLEI VFPAGDHVYPGLKTELHSMRSTLESIYkDaMRQCP LLGCGDKSVISRLSQEAERKSDNGTRKGLSELDTL FSRLEEYLHSRK
Research Topic
others
Uniprot ID
F5HC71
Gene Names
UL111A
Tag Info
NO-tagged
Expression Region
26-176aa
MW of Fusion Proten
17, 5
Sequence Info
Full Length of Mature Protein
Relevance
Functional viral IL-10 homolog. Can bind to the human IL-10 receptor and compete with human IL-10 for binding sites. Requires both subunits of the human IL-10 receptor complex to induce signal transduction events and biological activities. IL-10 signaling pathway has several immunosuppressive activities that are exploited by the virus. Inhibits TLR-induced type I interferon production in host plasmacytoid dendritic cells.
Reference
"Two novel spliced genes in human cytomegalovirus."
Akter P., Cunningham C., McSharry B.P., Dolan A., Addison C., Dargan D.J., Hassan-Walker A.F., Emery V.C., Griffiths P.D., Wilkinson G.W., Davison A.J.
J. Gen. Virol. 84:1117-1122(2003)
Purity
Greater than 90% as determined by SDS-PAGE.
Storage Buffer
Tris-based buffer, 50% glycerol
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Species
Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
Tag Information
N-terminal 10xHis-SUMO-tagged

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200ug
Lieferbar: In stock
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