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Recombinant Rabies virus Matrix protein(M)

Recombinant Rabies virus Matrix protein(M)

ArtNr	CSB-EP333055RJA-10
Hersteller	Cusabio
Menge	10ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Liquid or Lyophilized powder
Specific against	other
Konjugat/Tag	Myc
Purity	Greater than 85% as determined by SDS-PAGE.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
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Research areas	Others
Target / Protein	M
Biologically active	Not Test
Expression system	E.coli
Species of origin	Rabies virus (strain CVS-11) (RABV)
Uniprot ID	P25223
AA Sequence	MNVLRKIVKKCRDEDTQKPSPVSAPPYDDDLWLPP PEYVPLKELTSKKNMRNFCVNGEVKACSPNGYSFR ILRHILGSFNEIYSGNHRMIGLVKVVVGLALSGAP VPEGMNWVYKLRRTLIFQWADSRGPLEGEELEYSQ EITWDDDTEFVGLQIRVGARQCHIQGRIWCINSNS RACQLWSDMSLQTQRSEEDKDSSLLLE
Tag Info	N-terminal 10xHis-tagged and C-terminal Myc-tagged
Expression Region	1-202aa
Protein length	Full Length of Mature Protein
MW	28.1 kDa
Alternative Name(s)	Phosphoprotein M2
Relevance	Plays a major role in assembly and budding of virion. Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form. Inhibits viral transcription and stimulates replication. Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons
References	"Comparative sequence analysis of the M gene among rabies virus strains and its expression by recombinant vaccinia virus." Hiramatsu K., Mannen K., Mifune K., Nishizono A., Takita-Sonoda Y. Virus Genes 7:83-88(1993)
Purity	Greater than 85% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function	Plays a major role in assembly and budding of virion. Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form. Inhibits viral transcription and stimulates replication. Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons (By similarity).
Subcellular Location	Virion membrane, Peripheral membrane protein, Host endomembrane system, Peripheral membrane protein
Protein Families	Lyssavirus matrix protein family
Tag Information	N-terminal 10xHis-tagged and C-terminal Myc-tagged

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