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Recombinant Human Zinc finger protein 638(ZNF638),partial

Recombinant Human Zinc finger protein 638(ZNF638),partial

ArtNr	CSB-EP026909HU-1
Hersteller	Cusabio
Menge	1mg
Kategorie	Oncology Peptides & Proteins Recombinant Proteins By Organ Heart & Blood Cancer
Typ	Proteins Recombinant
Format	Liquid or Lyophilized powder
Specific against	other
Host	E.coli
Purity	Greater than 90% as determined by SDS-PAGE.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Cutaneous T-cell lymphoma-associated antigen se33-1,Short name:CTCL-associated antigen se33-1,Nuclear protein 220,Zinc finger matrin-like protein
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Research Areas	Others
Uniprot ID	Q14966
Gene Names	ZNF638
Organism	Homo sapiens (Human)
AA Sequence	TFATLNTKGNEGDTVRDSIGFISSQVPEDPSTLVT VDEIQDDSSDLHLVTLDEVTEEDEDSLADFNNLKE ELNFVTVDEVGEEEDGDNDLKVELAQSKNDHPTDK KGNRKKRAVDTKKTKLESLSQVGPVNENVMEEDLK TMIERHLTAKTPTKRVRIGKTLPSEKAVVTEPAKG EEAFQMSEVDEESGLKDSEPERKRKKTEDSSSGKS VASDVPEELDFLVPKAGFFCPICSLFYSGEKAMTN HCKSTRHKQNTEKFMAKQRKEKEQNEAEERSSR
Expression Region	1701-1978aa
Sequence Info	Partial
Source	E.coli
Tag Info	N-terminal 6xHis-SUMO-tagged
MW	47.2 kDa
Alternative Name(s)	Cutaneous T-cell lymphoma-associated antigen se33-1 Short name:CTCL-associated antigen se33-1 Nuclear protein 220 Zinc finger matrin-like protein
Relevance	Early regulator of adipogenesis that works as a transcription cofactor of CEBPs, controlling the expression of PPARG and probably of other proadipogenic genes, such as SREBF1 (By similarity). Binds to cytidine clusters in double-stranded DNA (PubMed:8647861). May also regulate alternative splicing of target genes during adipogenesis (By similarity).
Reference	A large DNA-binding nuclear protein with RNA recognition motif and serine/arginine-rich domain.Inagaki H., Matsushima Y., Nakamura K., Ohshima M., Kadowaki T., Kitagawa Y.J. Biol. Chem. 271:12525-12531(1996)
Purity	Greater than 90% as determined by SDS-PAGE.
Form	Liquid or Lyophilized powder
Buffer	If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20C/-80C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function	Early regulator of adipogenesis that works as a transcription cofactor of CEBPs, controlling the expression of PPARG and probably of other proadipogenic genes, such as SREBF1 (By similarity). Binds to cytidine clusters in double-stranded DNA
Subcellular Location	Nucleus speckle
Tag Information	N-terminal 6xHis-SUMO-tagged

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