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Recombinant Human Erythrocyte band 7 integral membrane protein(STOM)

Recombinant Human Erythrocyte band 7 integral membrane protein(STOM)

ArtNr	CSB-EP022862HU-1
Hersteller	Cusabio
Menge	1mg
Quantity options	1mg 10ug 100ug 20ug 200ug 50ug 500ug
Kategorie	Neuroscience Metabolism Diabetes Molecular Targets for Neuroscience Targets for Rodent Neurosciences Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Liquid or Lyophilized powder
Specific against	Human
Host	E.coli
Purity	Greater than 90% as determined by SDS-PAGE.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Protein 7.2b,Stomatin
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Research Areas	Neuroscience
Target / Protein	STOM
Biologically Active	Not Test
Expression System	E.coli
Species of origin	Homo sapiens (Human)
Uniprot ID	P27105
AA Sequence	MAEKRHTRDSEAQRLPDSFKDSPSKGLGPCGWILV AFSFLFTVITFPISIWMCIKIIKEYERAIIFRLGR ILQGGAKGPGLFFILPCTDSFIKVDMRTISFDIPP QEILTKDSVTISVDGVVYYRVQNATLAVANITNAD SATRLLAQTTLRNVLGTKNLSQILSDREEIAHNMQ STLDDATDAWGIKVERVEIKDVKLPVQLQRAMAAE AEASREARAKVIAAEGEMNASRALKEASMVITESP AALQLRYLQTLTTIAAEKNSTIVFPLPIDMLQGII GAKHSHLG
Tag Info	N-terminal 6xHis-SUMO-tagged
Expression Region	1-288aa
Protein Length	Full Length
MW	47.7 kDa
Alternative Name(s)	Protein 7.2b Stomatin
Relevance	Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity.
Reference	Stomatin interacts with GLUT1/SLC2A1, band 3/SLC4A1, and aquaporin-1 in human erythrocyte membrane domains.Rungaldier S., Oberwagner W., Salzer U., Csaszar E., Prohaska R.Biochim. Biophys. Acta 1828:956-966(2013)
Purity	Greater than 90% as determined by SDS-PAGE.
Form	Liquid or Lyophilized powder
Buffer	If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20C/-80C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function	Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity.
Subcellular Location	Cell membrane, Peripheral membrane protein, Cytoplasmic side, Cytoplasm, cytoskeleton, Cell membrane, Lipid-anchor, Cytoplasmic side, Membrane raft, Melanosome, Cytoplasmic vesicle
Protein Families	Band 7/mec-2 family
Tissue Specificity	Detected in erythrocytes (at protein level). Widely expressed.
Tag Information	N-terminal 6xHis-SUMO-tagged

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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CSB-EP022862HU-1-datasheet.pdf

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