Vergleich

Recombinant Pig Erythropoietin(EPO)

ArtNr CSB-EP007743PI-10
Hersteller Cusabio
Menge 10ug
Kategorie
Typ Proteins Recombinant
Format Liquid or Lyophilized powder
Specific against other
Host E.coli
Purity Greater than 90% as determined by SDS-PAGE.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Lieferbar
Research areas
Cardiovascular
Target / Protein
EPO
Biologically active
Not Test
Expression system
E.coli
Species of origin
Sus scrofa (Pig)
Uniprot ID
P49157
AA Sequence
APPRLICDSRVLERYILEAKEGENATMGCAESCSF SENITVPDTKVNFYAWKRMEVQQQAMEVWQGLALL SEAILQGQALLANSSQPSEALQLHVDKAVSGLRSL TSLLRALGAQKEAIPLPDASPSSATPLRTFAVDTL CKLFRNYSNFLRGKLTLYTGEACRRRDR
Tag Info
N-terminal 6xHis-B2M-tagged
Expression Region
27-194aa
Protein length
Full Length of Mature Protein
MW
32.6 kDa
Relevance
Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass.
References
"The porcine erythropoietin gene: cDNA sequence, genomic sequence and expression analyses in piglets."
David R.B., Blom A.K., Sjaastad O.V., Harbitz I.
Domest. Anim. Endocrinol. 20:137-147(2001)
Purity
Greater than 90% as determined by SDS-PAGE.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.
Subcellular Location
Secreted
Protein Families
EPO/TPO family
Tissue Specificity
Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.
Tag Information
N-terminal 6xHis-B2M-tagged

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10ug
Lieferbar: In stock
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