ArtNr |
CSB-EP007743PI-10 |
Hersteller |
Cusabio
|
Menge |
10ug |
Kategorie |
|
Typ |
Proteins Recombinant |
Format |
Liquid or Lyophilized powder |
Specific against |
other |
Host |
E.coli |
Purity |
Greater than 90% as determined by SDS-PAGE. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Lieferbar |
|
Research areas |
Cardiovascular |
Target / Protein |
EPO |
Biologically active |
Not Test |
Expression system |
E.coli |
Species of origin |
Sus scrofa (Pig) |
Uniprot ID |
P49157 |
AA Sequence |
APPRLICDSRVLERYILEAKEGENATMGCAESCSF SENITVPDTKVNFYAWKRMEVQQQAMEVWQGLALL SEAILQGQALLANSSQPSEALQLHVDKAVSGLRSL TSLLRALGAQKEAIPLPDASPSSATPLRTFAVDTL CKLFRNYSNFLRGKLTLYTGEACRRRDR |
Tag Info |
N-terminal 6xHis-B2M-tagged |
Expression Region |
27-194aa |
Protein length |
Full Length of Mature Protein |
MW |
32.6 kDa |
Relevance |
Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. |
References |
"The porcine erythropoietin gene: cDNA sequence, genomic sequence and expression analyses in piglets." David R.B., Blom A.K., Sjaastad O.V., Harbitz I. Domest. Anim. Endocrinol. 20:137-147(2001) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. |
Subcellular Location |
Secreted |
Protein Families |
EPO/TPO family |
Tissue Specificity |
Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals. |
Tag Information |
N-terminal 6xHis-B2M-tagged |
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